Comprehensive clinical services to drive faster, smarter drug, medical device, diagnostic and combination product development.

Is Your Trial Important?


Comprehensive clinical services to drive faster, smarter drug, medical device, diagnostic and combination product development.

Is Your Trial Important?


Comprehensive clinical services to drive faster, smarter drug, medical device, diagnostic and combination product development.

Is Your Trial Important?


Comprehensive clinical services to drive faster, smarter drug, medical device, diagnostic and combination product development.

Is Your Trial Important?


Combination Trials

More Experience in Combination Trials Than Any Other Partner

With decades of excellence in biopharmaceuticals, medical devices and in vitro diagnostics, Theorem is the industry authority in patient-centric combination product development and management. From creating robust clinical analytics and data visualization solutions, to honing the therapeutic and cross-functional expertise necessary to conduct intricate trials, our capabilities drive faster, smarter combination product development.

Combination Trial Expertise



EXPERTISE derived from conducting hundreds of trials across all major therapeutic areas for some of the world’s largest pharmaceutical and biotechnology companies.

CAPABILITIES for every phase of development from study startup and feasibility to supply to regulatory submission.

FLEXIBILITY to accommodate trials of every size and to access specific patient populations, including those in new and emerging markets.

Biopharmaceutical Expertise


Medical Device

EXPERTISE in development and regulatory affairs to execute successful medical device trials across all risk classifications and approval pathways globally.

CAPABILITIES in health economics to develop adjunctive reimbursement and safety surveillance programs, and ongoing marketing support.

FLEXIBILITY to develop primary devices as well as implantable devices (e.g., drug-coated or drug-eluting stents) and device-based drug delivery mechanisms.

Medical Device Expertise



EXPERTISE in medical device diagnostics, including in vitro diagnostic (IVD) and in vivo imaging, to develop reagents, instruments and systems.

CAPABILITIES including molecular diagnostics, immunoassay, hematology, flow cytometry and microbiology solutions to streamline entire development programs.

FLEXIBILITY from technologies and strategic alliances to identify sites and investigators that meet technical, statistical and practical requirements for a variety of device and diagnostics trials.

Diagnostics Expertise

theorem thumbs phone

A Moment’s Notice: Theorem THUMBS℠ Alert System

Theorem’s communicative, client-centered approach is not only valuable for you, it’s essential to the work we do. The Theorem THUMBS Alert System will give you the power to express your thoughts in seconds. By staying closely connected, we’re able to foresee needs, tailor solutions and prevent issues. This is the latest innovation proving that, at Theorem, nothing is more important than the work we do for you.


When Analytics Need to Be Your
Advantage, Think Theorem.

Essentially, clinical trials are about one thing: data. How you reach patients and collect, manage, interpret and prepare clinical trial data can be the difference between a successful trial and a costly failure.

Theorem is setting the standard for the way data is being used in clinical research with visual analytics tools and techniques that work in real time to identify meaningful information. When you need data to simplify complex trials, Theorem’s clinical analytics solutions are your advantage.


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Clinical Analytics

How We Think Differently

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Theorem Updates


Theorem's Angela Stokes Interviews President of BfArM Germany for Regulatory Rapporteur Journal

August 25, 2015
Angela Stokes, Theorem senior director of regulatory affairs clinical trial group, interviewed Prof. Dr. med Karl Broich, presiden...
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Chiltern Announces Agreement to Acquire Theorem Clinical Research

August 6, 2015
(London, U.K., and Wilmington, N.C.; August 6, 2015) — Chiltern, a leading global contract research organization (CRO), ...
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Theorem to Co-host Webinar on Reviving Trial Enrollment Levels With DAC Patient Recruitment Services

July 30, 2015
(King of Prussia, PA; July 30, 2015) – Theorem, a leading global contract research organization (CRO) that optimizes trial c...
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Theorem’s Jason Monteleone Named a Finalist for Philadelphia Business Journal's CFO of the Year Honor

July 13, 2015
Jason Monteleone, Theorem executive vice president and CFO, was named as one of the finalists for Philadelphia Business Journal...
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The Role of Companion Diagnostics in the Era of Personalized Medicine

June 30, 2015
Brian D. Bollwage, JD, Theorem’s vice president of global regulatory affairs, discusses personalized medicine and companion ...
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Theorem Clinical Research Teams Up With Decision Driver Analytics to Host Webinar on Mobile Medical Applications

June 10, 2015
(King of Prussia, PA; June 10, 2015) — Theorem Clinical Research, a leading global contract research organization (CRO) that...
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June 10, 2015
Anne Macek, MD, FAAP, Theorem’s senior medical director, wrote an article about developing medicines to treat rare diseases....
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Theorem Wins Two Productivity Awards

June 3, 2015
Theorem was recently awarded two CRO Leadership awards by Life Science Leader magazine. Theorem won the Productivity Award in the ...
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Theorem’s John Potthoff to Present on CRO/Sponsor Relationship Development at DIA

June 2, 2015
(King of Prussia, PA; June 2, 2015) — Theorem Clinical Research, a leading global contract research organization (CRO) ...
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Pain Week 2015

September 8-12, 2015
Las Vegas, NV
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The Regional Drug Development Asian Summit

September 8-9, 2015
Shanghai, China
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Outsourcing in Clinical Trials Nordics 2015

September 9-10, 2015
Copenhagen, Denmark
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Medidata Symposium 2015 – China

September 10, 2015
Beijing, China
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2015 ASA Biopharmaceutical Section FDA – Industry Statistics Workshop

September 16-18, 2015
Washington D.C.


Jeffrey L. Joseph

Current and Future Role of the Clinical Statistician in the World of Data Transparency

Session at 1:15 p.m. on September 17


Adam Hamm

Recent Innovations in the Development and Application of Statistical Designs for Early-Phase Oncology Trials

Session at 8:30 a.m. on September 18


Adam Hamm      

Common Statistical Issues FDA Encounters

Session at 12:45 p.m. on September 18


Jeffrey L. Joseph

Statistical Considerations in Evaluating Imaging-Based Devices

Session at 2:15 p.m. on September 18

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Arena Outsourcing in Clinical Trials New England 2015

September 16-17, 2015
Boston, MA
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ISPE’s European Investigational Products Conference

September 16-17, 2015
Braine I’Alleud, Belgiuim
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Society for Clinical Data Management (SCDM) 2015 Annual Conference

September 20-23, 2015
Washington, D.C.

Booth 309

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Bio 2 Business: Biotech Outsourcing Strategies 2015

September 22, 2015
London, United Kingdom
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